A Regenative Approach to Tarsal Tunnel Syndrome
Tarsal tunnel syndrome occurs when damaged or collapsed connective tissues surrounding the tibial nerve contribute to compression, often resulting in pain, tingling, or numbness. This study evaluated the use of Wharton’s Jelly (WJ) allografts to supplement these tissues in patients whose symptoms persisted despite standard conservative care.
Study Overview
Eight patients across four clinical sites received a single WJ allograft application after failing at least six weeks of standard care. Outcomes were assessed over a 90-day period using the Numeric Pain Rating Scale (NPRS) and the WOMAC functional index. All procedures adhered to FDA and AATB guidelines.
Results
No adverse events were reported. Over 90 days, patients experienced an average 59.43% improvement in NPRS pain scores and a 37.58% improvement in WOMAC functional scores. Improvements were observed consistently across the cohort.
Clinical Significance
By supplementing the connective tissues around the tibial nerve, Wharton’s Jelly may help support cushioning and structural stability in the tarsal tunnel region. These early findings support further research into WJ allografts as a minimally invasive option for patients with connective-tissue–related nerve compression.
Read the Full Study
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