AESTHETIC APPLICATIONS

The goal in regenerative aesthetics is to restore soft tissue that has been lost over time to regain a more youthful and fresher appearance. You know the vital role tissue health plays in the overall well-being of patients. Regenative Labs’ mission is to facilitate predictable patient outcomes by offering the highest quality human tissue allografts available.

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Regenerative medicine can help you look your best.

Aging decreases structural factors such as collagen and elastin leading to a degradation of structural morphology, position and ratios. A symmetrical face is considered more attractive, therefore face harmonization is one of the most sought-after techniques in Aesthetics. When connective tissue decreases the healthy volume diminishes and makes the physical appearance hallow and tired. Healthy tissue translates to a plump, hydrated and youthful, nourished skin and face structure.

What is an Aesthetics Structural Defect?

Aging skin and superficial soft tissue suffer from both structural and functional degradation over time. There are also intrinsic (age, gender, and genetics) and extrinsic factors such as drug interaction, food or beverages, smoking, malnutrition, environment and even the way you sleep must be considered.

“As a 55-year-old person, if you had to choose between a facelift and a total volume rejuvenation, the volume rejuvenation is probably better. The volume is hugely important because that loss of volume is what makes people look tired and hollow.”

-Dr. Kevin Welch, Board Certified General & Cosmetic Dermatologist

Additional Connective Tissue Supplementation Aesthetics Uses

With connective tissue supplementation, medical providers can address the problem at its source by inserting new, viable connective tissue ECM directly to the site of the breakdown, or defect (via syringe). The patient’s body can use the collagenic superstructure from the newly transplanted Wharton’s jelly as building blocks to fill voids or degradation in soft tissues. Ask your medical professional about Wharton’s jelly as an alternative to synthetic fillers that degrade over time.

Organic Fillers vs Synthetic

Revitalize inherent beauty by enhancing facial tissues with authentic, healthy tissue! Unlike synthetic fillers that only simulate connective tissue, this natural tissue becomes an integral part of your own body.

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Regenative Labs’ SecreText provides a better more natural option when compared to synthetic materials used as dermal fillers.

SecreText for Replacement Tissue

SecreText is used as replacement tissue suited for aesthetic applications. SecreText has higher concentrations of collagens, hyaluronic acid, and growth factors when compared to PRP. SecreText is processed from human tissue, donated following full-term C-section deliveries in accordance with the FDA.

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Study the latest innovations and the variety of options available to medical specialties.

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Commitment to Quality and Transparency

Regenative Labs is a leader in the field of regenerative medicine. Our commitment to quality and transparency is demonstrated by collecting data from patient outcomes and analyzing it for statistical significance, ensuring physicians make the most informed decision to facilitate the best possible outcomes for their patients.

From our retrospective data repository, you will witness improvements beginning at the 30-day mark.

LEARN About Wharton’s Jelly

About Wharton’s Jelly

Wharton’s Jelly (WJ) was initially characterized in 1656 by Thomas Wharton[1]. Advances in regenerative medicine have increased significantly throughout the past decade. Located between the blood vessels of the umbilical cord and the amniotic epithelium, WJ spans the entire length of the umbilical cord, providing protection, cushioning, and structural support [2,3].

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Since its initial discovery, there has been significant interest in the use of WJ in regenerative medicine applications[2].

Initial research centered on WJ as a cellular product, dependent on the metabolic activity of living cells to exert its primary function[3]. However, current research demonstrates that WJ exerts an effect independent of any cellular activity[3]. Initially classified as a mucoid connective tissue, we now know that WJ functions as an ideal system to transplant chemokine and growth factors, in addition to providing a biomechanical microarchitecture for collagen extracellular matrix formation in collagen-based defects[4].

Advantages of Wharton’s Jelly

This connective tissue contains high amounts of extracellular matrix components including collagen types I, III, and V, elastin, and fibronectin [1, 2]. Wharton’s jelly mainly provides cushioning and structural support to the umbilical cord but also contains a natural source of long-chain hyaluronic acid and numerous cytokines and growth factors. Studies have described placental tissues to be “immune privileged” as they rarely evoke an immune response in the body, reducing the risk of adverse reactions [4].

Structural Support

Wharton’s jelly provides a natural scaffold to facilitate cellular adhesion [1, 2].

CITATIONS:

1. Kim DW, Staples M, Shinozuka K, Pantcheva P, Kang SD, Borlongan CV. Wharton’s jelly derived mesenchymal stem cells: phenotypic characterization and optimizing their therapeutic potential for clinical applications. Int J Mol Sci. 2013 May 31;14(6):11692-712. doi: 10.3390/ijms140611692. PMID: 23727936; PMCID: PMC3709752.

2. Gupta A, El-Amin SF 3rd, Levy HJ, Sze-Tu R, Ibim SE, Maffulli N. Umbilical cord derived Wharton’s jelly for regenerative medicine applications. J Orthop Surg Res. 2020 Feb 13;15(1):49. doi: 10.1186/s13018-020-1553-7. PMID: 32054483; PMCID: PMC7017504.

3. Deus IA, Mano JF, Custódio CA. Perinatal tissues and cells in tissue engineering and regenerative medicine. Acta Biomater. 2020 Jul 1;110:1-14. doi: 10.1016/j. actbio.2020.04.035. Epub 2020 May 14. PMID: 32418650.

4. Jadalannagari S, Converse G, McFall C, Buse E, Filla M, Villar MT, Artigues A, MellotAJ, Wang J, Detamore MS, Hopkins RA, Aljitawi OS. Decellularized Wharton’s Jelly from human umbilical cord as a novel 3D scaffolding material for tissue engineering applications. PLoS One. 2017 Feb 21;12(2):e0172098. doi: 10.1371/journal. pone.0172098. Erratum in: PLoS One. 2017 Mar 7;12 (3):e0173827. PMID: 28222169; PMCID: PMC5319682.

CryoText Product Information

For more information about our Cryotext product, visit the link below.

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CODE LIST

Download the ICD-10 Code List to Identify Other Potential Use Sites.

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