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CONNECTIVE TISSUE SUPPLEMENTATION

Connective Tissue Supplementation is the practice of simply replacing missing or damaged tissue in the body with new, healthy, connective tissue.

Pain is merely a symptom of an underlying condition or injury.

Often, this breakdown in connective tissue is addressed with opiates or steroids to ease the patient’s discomfort.

When we experience pain, our body is sending us a message that something is wrong. Using steroids or opiates alone to address pain caused by injury masks the issue instead of addressing the root cause.

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Image of damaged articular cartilage (500nm) (knee)

IMPROVING QUALITY OF LIFE

With connective tissue supplementation, you have an opportunity to address the problem at its source by inserting new, viable connective tissue ECM directly to the site of the breakdown, or defect (via syringe). The patient’s body can use the collagenic superstructure from the newly transplanted Wharton’s jelly as building blocks to fill voids or defects in cartilage beds or other soft tissues.

Effectively, you can identify & address the root cause instead of treating symptoms, giving your patients a shot at long-term improvement in their quality of life.

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Leg with emphasis on Knee

WHAT DOES THIS LOOK LIKE FOR MY PRACTICE?

When a patient presents missing or damaged connective tissue after imaging, this homologous use justification appropriates homologous use for a connective tissue supplement to replace the missing or damaged tissue. Tissue supplementation is determined case-by-case but is generally a gradual process. Depending on the case, multiple applications may be necessary to achieve the desired clinical outcome.

For defects in large joints (hips, shoulders, knees), Cryotext™ is preferred because it has a higher concentration of tissue weight and will provide the most resistance to mechanical stress. For smaller defects in the face and scalp, SecreText™ is appropriate because of the lower concentration and smaller particulate size designed to be minimally invasive and flow through a 32-gauge needle.

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HOMOLOGOUS USE

Homologous use means the repair, reconstruction, replacement, or supplementation of a recipient’s cells or tissues with an HCT/P that performs the same basic function or functions in the recipient as in the donor.

As exhibited in the photo, Regenative Labs’ Wharton’s jelly after processing, is shown to be structurally similar, via electron microscopy, for homologous connective tissue supplementation or transplantation.

The structural similarities of Wharton’s jelly are shown to be similar in not only articular cartilage but other connective tissues found throughout the body.

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THREE-DIMENSIONAL ELECTRON MICROSCOPY OF 1. Post-processed Umbilical Cord Tissue (300nm) 2. Pre-processed Umbilical Cord Tissue (300nm) 3. Image of articular cartilage (500nm) (knee)

THREE-DIMENSIONAL ELECTRON MICROSCOPY OF


  1. Post-processed Umbilical Cord Tissue (300nm)
  2. Pre-processed Umbilical Cord Tissue (300nm)
  3. Image of damaged articular cartilage (500nm) (knee)

Don’t Just Take Our Word For It.

Listen to these three professional athletes talk about their results from using Wharton’s Jelly Tissue Allografts.

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Advantages of Wharton’s Jelly

Wharton’s jelly contains a natural source of long-chain hyaluronic acid and numerous cytokines and growth factors. It is a cryopreserved matrix that acts as a supportive scaffold for connective tissue repair. The matrix contains scaffolding proteins that have been shown to aid in tissue repair. It is utilized to provide a structured framework and support for connective tissue augmentation.

Wharton’s jelly does not use any material obtained directly from the embryo or fetus and is processed from human tissue, donated following full-term, c-section deliveries, in accordance with the FDA.

HOW WHARTON’S JELLY TISSUE ALLOGRAFTS ARE APPLIED

This is a connective tissue supplement intended for homologous use only, as described in 21CFR 1271.10(a). Structural connective tissue that is missing or damaged severely may require new or additional tissue to create conditions that encourage the stability of anatomic infrastructure. The Wharton’s jelly tissue allograft is applied directly to the site of the defect or injured area via syringe.

connective tissue supplementation

Our List of Products

CRYOTEXT™

CrytoText™ is our most concentrated, non-coded Wharton's Jelly or human umbilical cord product that is rich in cytokines, growth factors and scaffolding proteins. It acts as a replacement tissue that is intended to replace missing or damaged connective tissue.

SECRETEXT™

SecreText™ is our newest dose form of Wharton's Jelly intended for smaller defects. Its tissue size is best suited for aesthetic applications where volume is needed to cushion or support the affected area.

PROTEXT™

ProText™ is our most concentrated Wharton's Jelly connective tissue supplement. It is intended for homologous use only to replace or supplement missing or damaged tissue directly at the site of the structural defect.

Q4246

AMNIOTEXT™

AmnioText™ is a sterile, dehydrated human amniotic membrane allograft, intended for homologous use to cover and protect the recipient's tissues.

Q4247

CODE LIST

Download the ICD-10 Code List to Identify Other Potential Use Sites.

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Regenative Labs’ resources are divided into the following categories:

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Discover

Discover our catalogue of applications showcasing how Regenative Labs’ proprietary products can be used.

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STUDY

Study the latest innovations and the variety of options available to medical specialties.

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EXPLORE

Explore the detailed descriptions of our products, their make-up and development through our state-of-the-art process and to identify which products are best suited for your patients’ unique needs.

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Commitment to Quality and Transparency

Regenative Labs is a leader in the field of regenerative medicine. Our commitment to quality and transparency is demonstrated by collecting data from patient outcomes and analyzing it for statistical significance, ensuring physicians make the most informed decision to facilitate the best possible outcomes for their patients.

CryoText™ Product Information

For more information about our Cryotext product, visit the link below.

Pricing and PLACING AN order

For pricing or to place an order, login or setup an account to get immediate access to our MEDNGINE platform.

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If you have any further questions, please contact us. We look forward to speaking with you!