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Discover how Wharton’s jelly allografts can help you facilitate the best possible outcomes for your patients.

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Our shared goal is to address the root cause of the problem for patients in debilitating situations and partner to offer an effective and minimally-invasive option.

You know the vital role tissue health plays in the overall well-being of patients. Regenative Labs’ mission is to facilitate predictable patient outcomes by offering the highest quality human tissue allografts available.

LEARN About Wharton's Jelly

About Wharton’s Jelly

Wharton’s Jelly (WJ) was initially characterized in 1656 by Thomas Wharton[1]. Advances in regenerative medicine have increased significantly throughout the past decade. Located between the blood vessels of the umbilical cord and the amniotic epithelium, WJ spans the entire length of the umbilical cord, providing protection, cushioning, and structural support [2,3].

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Since its initial discovery, there has been significant interest in the use of WJ in regenerative medicine applications[2].

Initial research centered on WJ as a cellular product, dependent on the metabolic activity of living cells to exert its primary function[3]. However, current research demonstrates that WJ exerts an effect independent of any cellular activity[3]. Initially classified as a mucoid connective tissue, we now know that WJ functions as an ideal system to transplant chemokine and growth factors, in addition to providing a biomechanical microarchitecture for collagen extracellular matrix formation in collagen-based defects[4].

Advantages of Wharton’s Jelly

This connective tissue contains high amounts of extracellular matrix components including collagen types I, III, and V, elastin, and fibronectin [1, 2]. Wharton’s jelly mainly provides cushioning and structural support to the umbilical cord but also contains a natural source of long-chain hyaluronic acid and numerous cytokines and growth factors. Studies have described placental tissues to be “immune privileged” as they rarely evoke an immune response in the body, reducing the risk of adverse reactions [4].

Structural Support

Wharton’s jelly provides a natural scaffold to facilitate cellular adhesion [1, 2].

As a leader in regenerative medicine, we partner with countless physicians to bring these advancements and knowledge to the forefront of medicine today.

  • Regenative Labs is dedicated to being collaborative partners, driven by our shared goals of improving patient outcomes.
  • Regenative Labs is an FDA-registered and inspected HCT/P manufacturer.
  • Tissue engineering and regenerative medicine can help address complex medical challenges.

We invite you to join us today.

PRACTICE RESOURCES

We start at square one – giving you access to the resources needed to market effectively and compliantly to generate patient traffic in your clinic. A plethora of 3rd party resources to meet your specific business needs are available. Our technical writers will work with you to highlight what it is that you do for your patients.

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MARKETING SUPPORT

We have a variety of pre-made marketing materials (print & digital ads) designed to help you drive patient traffic in your clinic. The content for each ad has been carefully analyzed for compliance by one of our certified tissue bank auditors (CTBAs).

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CLINICAL SUPPORT

  • You will have a team of CRCs (Clinical Research Coordinators) dedicated to your success. They will assist you with onboarding, data submission, publication, and more. Our CRC team provides support every step of the way.
  • Development to review IFU & protocols
  • Collaborative practice onboarding with our research, finance, and marketing teams

Regenative Labs’ resources are divided into the following categories:

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Discover

Discover our catalogue of applications showcasing how Regenative Labs’ proprietary products can be used.

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STUDY

Study the latest innovations and the variety of options available to medical specialties.

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EXPLORE

Explore the detailed descriptions of our products, their make-up and development through our state-of-the-art process and to identify which products are best suited for your patients’ unique needs.

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Commitment to Quality and Transparency

Regenative Labs is a leader in the field of regenerative medicine. Our commitment to quality and transparency is demonstrated by collecting data from patient outcomes and analyzing it for statistical significance, ensuring physicians make the most informed decision to facilitate the best possible outcomes for their patients.

Don’t just take our word for it.

Hear from Attorney, Robert M. Castle, III, ESQ., about the ways Regenetive Labs goes above and beyond market standards to ensure patient and physician confidence through clinical excellence, innovation, and compliance.

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ProText™ and AmnioText™ Products

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CryoText™ and SecreText™ Products

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Regulatory Criteria for 361 Pathway

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CryoText™ Product Information

For more information about our Cryotext product, visit the link below.

Pricing and PLACING AN order

For pricing or to place an order, login or setup an account to get immediate access to our MEDNGINE platform.

DON’t HESITATE TO REACH OUT.

If you have any further questions, please contact us. We look forward to speaking with you!

CITATIONS:

1. Kim DW, Staples M, Shinozuka K, Pantcheva P, Kang SD, Borlongan CV. Wharton’s jelly derived mesenchymal stem cells: phenotypic characterization and optimizing their therapeutic potential for clinical applications. Int J Mol Sci. 2013 May 31;14(6):11692-712. doi: 10.3390/ijms140611692. PMID: 23727936; PMCID: PMC3709752.

2. Gupta A, El-Amin SF 3rd, Levy HJ, Sze-Tu R, Ibim SE, Maffulli N. Umbilical cord derived Wharton’s jelly for regenerative medicine applications. J Orthop Surg Res. 2020 Feb 13;15(1):49. doi: 10.1186/s13018-020-1553-7. PMID: 32054483; PMCID: PMC7017504.

3. Deus IA, Mano JF, Custódio CA. Perinatal tissues and cells in tissue engineering and regenerative medicine. Acta Biomater. 2020 Jul 1;110:1-14. doi: 10.1016/j. actbio.2020.04.035. Epub 2020 May 14. PMID: 32418650.

4. Jadalannagari S, Converse G, McFall C, Buse E, Filla M, Villar MT, Artigues A, MellotAJ, Wang J, Detamore MS, Hopkins RA, Aljitawi OS. Decellularized Wharton’s Jelly from human umbilical cord as a novel 3D scaffolding material for tissue engineering applications. PLoS One. 2017 Feb 21;12(2):e0172098. doi: 10.1371/journal. pone.0172098. Erratum in: PLoS One. 2017 Mar 7;12 (3):e0173827. PMID: 28222169; PMCID: PMC5319682.

DISCLAIMER

Regenative Labs is an FDA-registered and inspected HCT/P manufacturer. We operate under strict compliance with all federal and state regulations.

Click here to download a copy of our Tissue Establishment Registration. 

Regenative Labs is an FDA registered and inspected tissue bank which follows all Good Tissue Practice guidelines per FDA 21 CFR 1271 of the PHS act.